Chemical Synthesis and Purification of Oligonucleotides

نویسنده

  • Gobind Khorana
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A Biotechnological Perspective on The Affinity Magnetic Separation and Purification Based on Oligonucleotides

The rapidly growing field of biotechnology has created a critical need for simple, fast andhigh-throughput processes for the separation and purification of biomolecules from biologicalmatrices. In recent years, several bioseparation techniques have been proposed as advancedalternatives to the classical separation methods. These modern processes emphasize ultrahighselective and sensitive analysi...

متن کامل

Specific Inhibition of the Expression of the Promyelocytic Leukemia (PML) Protein by Anti-Sense Oligonucleotides

In the present study, using anti-sense oligonucleotides the inhibition of expression of the PML protein hasbeen investigated. The anti-sense oligonucleotides were designed against the translation initiation site ofthe PML gene, and their effects were investigated on cellular growth and DNA synthesis. Incubation of normalhuman fibroblast cells with the anti-sense oligonucleotid...

متن کامل

Recent Methods for Purification and Structure Determination of Oligonucleotides

Aptamers are single-stranded DNA or RNA oligonucleotides that can interact with target molecules through specific three-dimensional structures. The excellent features, such as high specificity and affinity for target proteins, small size, chemical stability, low immunogenicity, facile chemical synthesis, versatility in structural design and engineering, and accessible for site-specific modifica...

متن کامل

Synthesis and purification of Carbon nanotubes

In this study, multi wall carbon nanotubes (MWCNTs) were synthesized by Chemical vapor deposition (CVD) method using two different catalysts (Fe nanoparticles) and (Ni nanoparticles) with  two different substrates: Quartz and Alumina. Acetylene gas was used as a carbon source and Argon as a carrier gas at different temperatures and different times to study the effects of these parameters on CNT...

متن کامل

Synthesis and purification of Carbon nanotubes

In this study, multi wall carbon nanotubes (MWCNTs) were synthesized by Chemical vapor deposition (CVD) method using two different catalysts (Fe nanoparticles) and (Ni nanoparticles) with  two different substrates: Quartz and Alumina. Acetylene gas was used as a carbon source and Argon as a carrier gas at different temperatures and different times to study the effects of these parameters on CNT...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2011